Acetaminophen and codeine may cause serious side effects. Call your doctor at once if you have: high levels of serotonin in the body--agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.

Acetaminophen and codeine is a combination medicine used to relieve moderate to severe pain. Acetaminophen and codeine may also be used for purposes not listed in this medication guide. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Drug information provided by: Merative, Micromedex ® Acetaminophen and codeine combination is used to relieve mild to moderate pain. Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time.

This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (acetaminophen and codeine tablets) is refilled. If you have any questions about this medicine (acetaminophen and codeine tablets), please talk with the doctor, pharmacist, or other health care provider.