Common side effects

• Drowsy
• Dizziness
• Acute cognitive impairment
• Excitement
• Symptoms of anxiety
• Nightmares
• Depression
• Constipation
• Syncope
• Vertigo
• Insomnia
• Lethargy
• Headache disorder
• Nausea
• Vomiting
• Nervousness
• Irritability

If any of these effects persist or worsen, tell your doctor or pharmacist promptly

• Nausea
• Vomiting
• Abdominal pain
• Constipation
• Dry mouth
• Shaking
• Shortness of breath
• Increased urination
• Lightheadedness
• Dizziness
• Drowsiness
• Trouble sleeping

Tell your doctor right away if any of these unlikely but serious side effects occur

• Mental/mood changes
• Fainting
• Seizures
• Fast/irregular heartbeat

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including

• Rash
• Itching/swelling
• Severe dizziness
• Trouble breathing

Other things to note

• To reduce your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

• Do not use 2 weeks before delivery in pregnancy
• May reduce effectiveness of hormone contraceptives
• May make you drowsy or dizzy. Drive with caution
• Avoid drinking alcohol
• Do not use with other acetaminophen products.
• Review all drugs you are taking with your doctor
• Call MD if new abdominal pain/yellowing eyes/skin
• For capsule products : Call Dr before increasing dose or frequency.
• For solution, oral products : Measure dose using a dosing spoon/cup/syringe.

• May cause drowsiness. Alcohol and marijuana may intensify this effect. Use care when operating a vehicle, vessel (e.g., boat), or machinery.
• Contains Acetaminophen. Don't use with other drugs that contain Acetaminophen (prescription or nonprescription) unless doctor approves. Too much can cause liver damage
• Do not drink alcoholic beverages when using this medication.
• Using more of this medication than recommended may cause serious breathing problems.
• If you are pregnant or considering becoming pregnant you should discuss the use of this medication with your doctor or pharmacist.
• May cause dizziness
• This medication can interfere with the effectiveness of birth control pills. Consult your doctor or pharmacist.

Before taking this medication, tell your doctor if you've had:

• Severe breathing problems (such as bronchopneumonia)
• A certain enzyme disorder (porphyria)
• Liver disease
• Kidney disease
• Personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol)
• Mental/mood disorders
• Abdominal/stomach problems (such as stomach ulcer)

Products that may interact with this drug include:

• Darunavir
• Sodium oxybate
• Drugs affecting liver enzymes that remove this medication from your body (such as macrolide antibiotics including erythromycin, cimetidine, disulfiram, valproic acid, fluvoxamine, MAO inhibitors including isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine)
• Isoniazid
• Lithium
• Phenothiazines (such as chlorpromazine)