A testing dose was unnecessary, Novartis believed, given that valsartan 320mg (160mg twice a day) had been tested in heart failure and with a 1:1 ratio with sacubitril. "I had nothing to learn ...
or 320 mg valsartan daily; 200 mg AHU377 daily; or placebo. Dosages were chosen so that patients treated with the low, medium, and high doses of LCZ696, respectively, would have the same ...
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