This anaerobic spore-forming bacterium thrives in the intestines and can cause severe symptoms, ranging from mild diarrhea to life-threatening pseudomembranous colitis ... of C. difficile and its ...

Aims—To examine whether treatment with intravenous immunoglobulin might be effective in patients with severe pseudomembranous colitis unresponsive to standard ... Methods—Antibodies against C ...

The findings come from two large phase 3 clinical trials—MODIFY I and MODIFY II—designed to determine the efficacy of the drug bezlotoxumab alone or in combination with the drug actoxumab for the ...

Learn about C. diff testing, treatment, precautions and what to expect ... These infections may cause diarrhea and colitis (chronic inflammation of the colon). Fecal matter (poop) contaminated ...

Mild Clostridium difficile infection (CDI; stool frequency <four-times daily; no signs of severe colitis), clearly induced ... immediately if this occurs. Treatment for an initial episode and ...

Further, patients who make it through the severe diarrhea, nausea, fever and colitis C. difficile can cause are not necessarily in the clear: One in six will develop another C. diff infection ...

Purpose The pharmacology, clinical efficacy, safety, dosage and administration, and place in therapy of fidaxomicin for the treatment of Clostridium difficile infection (CDI) are reviewed.

Funding This work was supported by a pilot and feasibility study grant (#29122) from the UCLA-CURE Center, a Crohn's and Colitis Foundation of America Research Fellowship (#1406) and a Career ...

The patient had undergone a staged total proctocolectomy with ileal-pouch–anal anastomosis and a loop ileostomy 8 months previously to treat her ... tests for C. difficile were not performed ...

The research of Cuong C. Nguyen, M.D., is related to the application ... of luminal and pancreatic conditions. He also studies the treatment and prevention of Clostridium difficile colitis and ...

Pardi, M.D., focuses on the clinical features, epidemiology and treatment of inflammatory bowel disease, specifically microscopic colitis, also known as lymphocytic colitis or collagenous colitis; ...