Preclinical studies and early clinical trials have shown that the anticancer agent tamoxifen, a relatively selective PKC inhibitor that can cross the blood–brain barrier, exerts an antimanic ...
Currently approved drugs in the USA in this class include tamoxifen citrate (e.g., Nolvadex®), raloxifene hydrochloride (Evista®) and toremifene (Fareston®), which is chemically related to and ...
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