In a peer-reviewed Perspective (review) article, researchers at the University of Nebraska Medical Center have uncovered concerning evidence that commonly prescribed medications may interfere with ...
Fieser, L. F., and Fieser, M., Natural Products Related to Phenanthrene (third ed.), 204 (Reinhold, New York, 1949). Fieser, L. F., and Fieser, M., Steroids, 177 ...
This is particularly concerning because the brain requires precise sterol regulation for proper development and function." Professor Károly Mirnics, lead author of the review The research reveals ...
Mammalian HMG-CoA reductase (HMGCR), the rate-limiting enzyme of the cholesterol biosynthetic pathway and the therapeutic target of statins, is post-transcriptionally regulated by sterol-accelerated ...
Diagnostic testing for various genetic lipid disorders including Smith-Lemli-Opitz syndrome (SLOS), cerebrotendinous xanthomatosis (CTX), and sitosterolemia is offered through the CAP/CLIA accredited ...
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Microarray gene expression profiling further revealed correlated expression changes including significant downregulation of RNAs responsible for sterol biosynthesis. Whereas mutant huntingtin ...
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