Overall, minocycline has a higher rate of side effects than other tetracycline antibiotics. Taking an extended-release (ER) product can lower the risk of side effects. Minocycline is the only ...

A low-dose (40 mg) modified formulation of minocycline hydrochloride (DFD-29) was better tolerated and more effective than doxycycline and placebo in patients with moderate to severe ...