The theory behind leucovorin's use for autism postulates that some children have a blockage in the transport of folic acid into the brain that potentially contributes to neurological symptoms.

If you are given too much (overdose) If you are given too much folinic acid, you may experience some of the effects listed under "Side Effects" below. Your doctor has information on how to ...

Leucovorin is currently prescribed to ease the side effects of cancer chemotherapy ... also known as folinic acid, into the brain. Enzymes in the brain convert leucovorin into the active form ...