Quarterback Brock Purdy threw for 255 yards and three touchdowns en route to leading the San Francisco 49ers to a 36-24 road ...

San Francisco spent the week answering questions about a slow start to the season before sending its strongest message to ...

San Francisco 49ers running back Christian McCaffrey, who has missed the entire season due to bilateral Achilles tendinitis, ...

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Watch highlights from the Week 6 matchup between the San Francisco 49ers and the Seattle Seahawks during the 2024 NFL season.

The San Francisco 49ers have been practicing in temperatures exceeding 90 degrees this week. Sunday's game against the ...

San Francisco 49ers running back Jordan Mason injured his left shoulder in the second quarter of the Week 6 Thursday night ...

The San Francisco 49ers (2-3) are visiting the Seattle Seahawks (3-3) at Lumen Field, in a battle for first place in the NFC West. You can find more injury and roster news here and here.

Week 6 in the NFL kicks off from Lumen Field as the Seattle Seahawks are set to host the San Francisco 49ers in an NFC West ...

Prime Video has taken a strong political stance over 'Thursday Night Football' as they have refused to show political ads.

Brock Purdy threw a touchdown pass, Fred Warner returned an interception for a score and the San Francisco 49ers snapped a two-game skid by beating the New England Patriots 30-13 on Sunday.

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 loss to the Arizona Cardinals, who went ahead on Chad Ryland’s 35-yard ...