Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis.

Scientists at St. Jude Children’s Research Hospital have uncovered the mechanism by which retinoic acid selectively kills ...

For nearly 50 years, doctors have known that the drug retinoic acid helps treat neuroblastoma, a type of solid tumor that ...

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...

Retinol and retinol esters take a few ‘conversions’ within the skin to become retinoic acid, while retinol takes two ...

When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10-15%. However, this effect was only evident in post ...

Retinoic acid (RA) signalling is important for the maintenance and regeneration of central nervous system. The signalling pathway acts via the nuclear receptors, the retinoic acid receptors (RARs) and ...

Retinoic acid (RA) is one of several molecules that pattern vertebrate embryos by forming an anterior to posterior (A–P) concentration gradient. The issue of whether RA is a classical morphogen ...

Topical retinoids (for example, tretinoin) and retinoid analogues (for example, adapalene and tazarotene) help normalize hyperkeratinization and have demonstrated significant anti-inflammatory ...

YourChoice Therapeutics, Inc., pioneering hormone-free family planning products, announced today that Communications Medicine, a Nature Portfolio journal, has published a peer-reviewed paper on the ...