If you have nocturnal (nighttime) leg cramps, your doctor might prescribe quinine (Qualaquin)-even though the U.S. Food and Drug Administration has approved it for only one purpose: to treat ...

But the FDA has issued repeated warnings against using quinine to prevent or treat leg cramps because it may cause serious side effects, including severe anemia, bleeding and kidney damage.

Quinine Quinine tablets are a common treatment. Quinine often reduces the number and severity of leg cramps, but may not stop them altogether. One tablet at bedtime is the normal dose. A four week ...