The joint most affected by pseudogout is the knee, followed by the wrist. The hand joints and the joint at the base of the big toe might also become inflamed. If the big toe is inflamed ...

People with Kelley-Seegmiller syndrome or Lesch-Nyhan syndrome may lack an enzyme that helps control uric acid levels. Pseudogout is a type of arthritis that causes pain, redness, heat, and swelling ...