A new study reports that mirodenafil, a newly developed oral phosphodiesterase type 5 (PDE5) inhibitor, is an efficacious and safe treatment for erectile dysfunction (ED). Many men with ED ...

Phosphodiesterase-5 inhibitors (sildenafil, vardenafil, tadalafil) enhance nitric oxide production and can cause potentially fatal hypotension when used in combination with nitrates. Nitrates ...

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Objective: Given the therapeutic and non-therapeutic use of the tadalafil, (phosphodiesterase-5 inhibitor, PDE-5i), we examined its effects on anaerobic performance indices. Methods: In total, 12 well ...