Third-generation oral contraceptives are an association of low-dose ethinyl estradiol and ... MR = Mineralocorticoid receptor; PR = Progesterone receptor. The relative binding affinity (%) of ...
Estrogen and progesterone combined in OCs act in a synergistic ... SHBG when given in proper doses and in combination with low-dose ethinyl estradiol, resulting in reduction of free testosterone.
Natural progesterone was hard to come by ... Unless researchers could find a way to produce a highly effective synthetic oral dosage of the hormone, the treatment would remain impractical.
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