The prescription version of Nexium is used for similar conditions as other PPIs, including erosive esophagitis, GERD, Zollinger-Ellison syndrome, and H. pylori infections. It can also be ...

PPIs are among the highest-selling classes of drugs in the U.S., with $9.5 billion in sales last year, and one of them, Nexium, was the top-selling of all drugs, earning nearly $6 billion in 2012 ...

Drugs like Nexium, Prevacid, and Prilosec are called proton pump inhibitors, or PPIs, and they've been linked to a bigger risk for dementia. PPIs reduce the amount of acid that your stomach makes.