That said, both minocycline and doxycycline can interact with the following medications: There are a few differences to note: Isotretinoin, an acne medication, should not be taken with minocycline.

A low-dose (40 mg) modified formulation of minocycline hydrochloride (DFD-29) was better tolerated and more effective than doxycycline and placebo in patients with moderate to severe ...

Participants were randomized to either daily minocycline hydrochloride (40 mg); doxycycline ... patients using minocycline ...