Introduction Colchicine, commonly classified as an anti-inflammatory agent, is a mainstay for the treatment of gout and a second-line therapy ... Conclusion Long-term prophylaxis with low-dose ...

Conclusion No significant reduction in the median level of hsCRP was observed but all were lower in colchicine arm, consistent with prior data. The totality of evidence supports the need for a ...

Recommendations for medications and lifestyle modifications to treat gout are based on new evidence ... Among other points, they clarify the use of medications that lower uric acid levels and the use ...

Two agents target the IL-1β pathway: Canakinumab, an expensive monoclonal antibody, directly inhibits this cytokine; in Europe, it is approved for patients with refractory gout ... (low dose colchcine ...

Among the recommendations for future research developed through the Delphi rounds was the optimal dose ... two of colchicine at the first sign of 'the tingle'). For those with acute gout of ...

bu.edu Objective To examine the association between cardioprotective use of low-dose aspirin and the risk of recurrent gout attacks among gout patients. Methods We conducted an online case-crossover ...

There is strong evidence from large randomized clinical trials that colchicine 0.5mg daily can alter the progression of coronary atherosclerosis along with lipid lowering and anti-thrombotic therapies ...

talk to your doctor about increasing your dose of allopurinol. It often takes six to 12 months after the uric acid level is suppressed below 6.0 mg/dl for symptoms of gout to stop. So it’s important ...

“It may be effective in preventing the train from leaving the station,” she said as supported by observational data in gout cohorts ... said he uses low-dose colchicine for the secondary ...