Medically reviewed by Matthew Wosnitzer, MD Erectile dysfunction (ED) is an inability to achieve or maintain an erection ...

Research has shown L-arginine supplements taken in combination with ED medications like PDE5 inhibitors ... topically as a gel or cream, or intravenously in a clinical setting.

Experts still don’t know how effective L-arginine supplementation is for ED. But limited research seems to suggest that it plays a role in combination with other ED drugs, such as: More research ...