While a mild itch is usually no biggie, a persistent itch could be pruritus ani (aka the medical name for anal itching). It ...

“Persistent itching in your hands and feet, especially at night, could point to more than just dry skin. When bile salts back up into your tissues, it causes this uncomfortable sensatio ...

Evolutionarily, that stronger, cleaner itch signal at night might have served us well ... the first thing a dermatologist usually does is look between the toes to see if there’s redness ...