Combining an ACE inhibitor with an ARB should be discouraged in these patients. Pfeffer MA et al. for the Valsartan in Acute Myocardial Infarction Trial Investigators. Valsartan, captopril ...

Only 7% of the patients enrolled in Val-HeFT were not on ACE inhibitors, but these patients showed significant improvement with addition of valsartan. Only 35% of enrolled patients were on ...

Soon after, other combinations were being tested in the clinic, such as ACE inhibitors and diurectics (lisinopril and hydrochlorothiazide); ARBs and diuretics (losartan or valsartan and ...

The earlier trial also showed advantages over enalapril on hospitalisation and death rates when patients switched from an ACE inhibitor – enough to get Novartis’ drug included in treatment ...

as “the putative mediator of angioedema induced by ACE inhibitors ... the effectiveness and safety of LCZ696 with that of valsartan in the reduction of blood pressure. The participants ...

[Jernberg 2018;1a] Medical therapy initiated before hospital discharge may include angiotensin converting enzyme inhibitors, angiotensin receptor blockers, sacubitril/valsartan (Entresto ...