It is an effective pain reducer and considered generally safe, but in high doses or in people with certain health conditions, it can cause serious side effects, including liver damage. These unwanted ...

Is it safe to take acetaminophen? Yes, it's usually safe when taken according to the directions on the label. But taking more than that can cause liver damage, liver failure, or even death.

NSAIDs can pose a risk to your kidney health. But while acetaminophen may be safer, all pain medications should be taken with a doctor’s supervision if you have kidney disease. It’s almost a ...