Biohaven Reports Positive Degrader Data Achieving > 80% Sustained Reductions in Total IgG with Potential First-in-Class BHV-1300
Biohaven Ltd. (NYSE: BHVN) ("Biohaven"), a global clinical-stage biopharmaceutical company focused on the discovery, ...
Medscape2mon
Role of IgG Antibodies in Association With Placental Function and Immunologic Diseases in Human Pregnancy
the immunology of human pregnancy and the role of the placenta in providing the fetal tissue with antibodies (IgG and its subclasses 1–4), which are required for the passive immunization of the ...
BMJ18d
Influence of ultra-endurance exercise on immunoglobulin isotypes and subclasses
1 Department of Sport and Physical Rehabilitation Sciences ... To determine exercise induced changes in the adaptive immune system by measuring the immunoglobulin isotype and subclass response to an ...
Morningstar14d
Biohaven Reports Positive Degrader Data Achieving > 80% Sustained Reductions in Total IgG with Potential First-in-Class BHV-1300
The rational design of BHV-1300 enables degradation of the autoantibodies causing Graves' disease, known to be of the IgG1 subclass ... IgG of up to 84%, with a median reduction of 80% (Figure 1).
Medscape14d
Role of IgG Antibodies in Association With Placental Function and Immunologic Diseases in Human Pregnancy
In the human, the placenta is the predominant route of IgG transfer in the maternal-to-fetal direction; the immune protection provided by maternal antibodies is essential for newborns during the ...