Many epidemiological studies have implicated hyperuricemia as an independent risk factor for cardiovascular morbidity. Gout, the clinical manifestation of hyperuricemia, has rarely been studied in ...

Gout is a form of arthritis caused by a buildup of uric acid crystals in a joint. It causes sudden attacks of pain, swelling, redness, and stiffness, usually in one joint, especially the big toe. Gout ...

MANILA, Philippines — After decades of studies, researchers from the University of the Philippines Manila (UPM) have ...

Inflammatory arthritis in patients with gout can usually be treated with drugs that counter hyperuricemia. Treatment fails in some patients, however, so a second-line therapy is desirable.

Purpose. The pharmacology, pharmacokinetics, clinical efficacy, and safety of febuxostat are reviewed. Summary. Febuxostat is a novel non-purine selective inhibitor of xanthine oxidase for the ...

The following is a summary of “Nonlinear association of cardiometabolic index with hyperuricemia: insights from the NHANES 1999-2018 study,” published in the March 2025 issue of Frontiers in ...

Hyperuricemia (HU), characterized by elevated uric acid (UA) levels in the blood, is a global health concern associated with various conditions, including cardiovascular diseases, gout ...

BACKGROUND: Uric acid may be a true mediator of renal disease and progression. However, epidemiological evidence for the significance of serum uric acid levels on the risk for developing end-stage ...