Glipizide/metformin HCl; 2.5mg/250mg, 2.5mg/500mg, 5mg/500mg; tabs. Adjunct to diet and exercise in type 2 diabetes, as initial therapy or as second-line therapy when response to a sulfonylurea or ...
The longer-acting agents (e.g. chlorpropamide, glyburide [glibenclamide], and sustained-release glipizide) are more likely to cause hypoglycemia than glipizide, glimepiride, and gliclazide.
The APPROACH trial 1 evaluated the effects of rosiglitazone compared with those of glipizide, an insulin-providing drug, on coronary atherosclerosis in a population with known coronary heart disease.
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