Appropriate dosage determination for aminoglycosides helps to achieve desirable levels of drug in the blood, thereby reducing the probability of ototoxicity, nephrotoxicity, and treatment failure.

Purpose: The development of two nomograms to predict dosing intervals for gentamicin in neonates based on one gentamicin concentration is described. Methods: Pooled data from three retrospective ...

Gentamicin sulfate 40mg/mL; IM, or IV inj after dilution; contains sulfites. Obesity: Base dose on lean body mass. Usual duration 7–10 days. 1mg/kg IM or IV every 8 hours; max 5mg/kg/day.