Preliminary results from a randomized, phase II trial have shown that the transdermal estrogen patch Fem7 ® (Merck KGaA, Darmstadt, Germany) can suppress testosterone to castrate levels in men ...

Low-dose transdermal patches and gels delivering estradiol may promote endometrial ... of FDA-approved testosterone gels approved for men. Long-term studies are needed to examine the safety ...

However, recently emerging evidence has suggested that estrogen also has important effects on bone health in men. Almost 20 years ago, Smith and colleagues reported a 28-year old man with a bone ...

and younger men (aged ≤56 years at baseline) were analyzed separately, the association between high estradiol levels and low risk of cardiovascular disease was only present in older men.