Medicare Part D prescription drug plans may cover estradiol cream. A person can check with their plan to confirm coverage.

For people with prescription drug coverage, anecdotal evidence suggests the cost of a tube of estradiol cream in 2025 is around $25 to $50. However, various factors can affect the cost of ...

If you’re enrolled in Medicare Advantage (Part C), estradiol cream may be covered if your plan offers prescription drug (Part D ... coinsurance or copayment cost. It’s important to check ...