Abstract: In conventional DNA synthesis machines, usually many strands are synthesized in parallel by iterating through a supersequence s and adding in each cycle the next nucleotide to a programmable ...
These machines used fluorescent dyes to tag each ... Over time, sequencing technology (and DNA synthesis technology) advanced with more sophisticated separation strategies, alternative ...
However, the conditions for DNA synthesis are rarely ideal, with several obstacles challenging the DNA replication machinery (Branzei & Foiani 2007; Heller & Marians 2006; Lambert, Froget & Carr ...