Unfortunately, trends are rarely as simple as they appear and may have people jumping into action before learning what ...

In such instances, cortisol blocker supplements can be extremely beneficial. Cortisol blocker supplements are designed to reduce the production of cortisol in the body, helping to manage stress ...

If you experience chronic stress and exhaustion that's affecting your daily life, it may be a sign that something deeper is going on, such as cortisol imbalance. Both high and low levels of ...

If you’ve scrolled through social media lately, you may have seen some chatter about cortisol—a stress hormone—and its supposed villainous effects on your body. Negative effects of cortisol ...

Cortisol is the word of the moment in the wellness world. Over on TikTok, there are over 277,000 videos on the term – and very few of them are positive. Most discussions around the hormone are ...

Each time a person undergoes stress the brain releases cortisol hormones. Cortisol binds to glucocorticoid receptors and tells the body to prepare its “fight-or-flight” response. This hormone also ...

Xanamem selectively inhibits the activity of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) (Fig. 1), an enzyme that converts inactive cortisone into its active form cortisol; 11β-HSD1 is ...

Recorlev is a cortisol synthesis inhibitor approved for the treatment of endogenous hypercortisolemia in adult patients with Cushing’s syndrome. Its product also includes Ogluo which is used for ...

In women with the polycystic ovary syndrome (PCOS), cortisol production rate is probably normal, although adrenal androgens can be overproduced in a subset of affected women. Cortisol metabolism ...

Expert Rev Endocrinol Metab. 2013;8(2):183-193. Mitotane reduces cortisol synthesis through the inhibition of 11B-hydroxylase, 18-hydroxylase, 3-α hydroxylase, hydroxysteroid dehydrogenase and ...