Purpose. The management of loop diuretic resistance in the intensive care unit (ICU) is reviewed. Summary. Volume overload, a common complication of fluid resuscitation, is frequently encountered ...

The FDA has accepted for review the NDA for bumetanide nasal spray for edema associated with CHF, as well as hepatic and renal disease.

[23] Electrolyte imbalance, particularly hypokalemia, is the most common adverse effect of loop diuretics. Through this mechanism, diuretics may increase mortality (especially arrhythmic deaths).

They are mainly comprised of five types, including thiazides, loop diuretics, potassium-sparring ... than first‐line ...