Medically reviewed by Lindsay Cook, PharmD Xyzal (levocetirizine) and Zyrtec (cetirizine) are antihistamines taken to relieve allergy symptoms such as sneezing, runny nose, itchy eyes, and hives.

Key differences between Zyrtec and Zyrtec-D include their active ingredients, the minimum age at which they can be used, purchasing restrictions, and available dosage forms. Moreover, because it ...