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Sildenafil citrate is a selective and potent inhibitor of phosphodiesterase type 5 (PDE5). PDE5 is a cyclic guanosine monophosphate (cGMP) specific degrading enzyme that is highly present in the ...

Methods: This randomised, double blind (DB), placebo controlled, flexible dose study with an open label extension (OLE) assessed efficacy, QoL, and safety of sildenafil citrate in men with MS and ED.