Background: Buspirone is a partial 5-HT 1A receptor agonist. Animal studies have shown that modulation of serotoninergic transmission at the 5-HT 1A receptor can induce analgesia in acute pain models.
Objective: To compare the anxiolytic effects of mexazolam with those of alprazolam in patients with generalised anxiety disorder ... in the management of GAD are buspirone, benzodiazepines ...