Interactions can also occur if you have certain ... can increase the risk of side effects from Lexapro and tramadol buspirone — can raise the risk of side effects from Lexapro and buspirone ...
Background: Buspirone is a partial 5-HT 1A receptor agonist. Animal studies have shown that modulation of serotoninergic transmission at the 5-HT 1A receptor can induce analgesia in acute pain models.