Large, bruise-like lesions that look purplish red on light skin and brownish black on dark skin occur. There may also be swelling that begins in the hands and feet and progresses to the arms and legs.

Such agents have been associated with bleeding events; the product information for Meridia ® (sibutramine, Abbot Laboratories, IL, USA) states that bruising occurred in 0.7% of sibutramine ...