The four selected RCTs compared antiseptics to metronidazole or clindamycin. In two studies control treatment consisted of a single oral dose of 2 g metronidazole, in one study of a 7-day regime ...
The precise mechanism of action of metronidazole is unclear. Infuse over 1hr. Anaerobic infections: 15mg/kg (loading dose), then 7.5mg/kg every 6hrs for 7–10 days; max 4g/24hrs. Bone/joint ...