People with acid reflux often rely on acid-reducing medications to ease symptoms. Depending on the severity of your symptoms, over-the-counter (OTC) and prescription options are available.

For the antihistamine desloratadine, in vitro studies have revealed it to be a highly potent H 1-receptor antagonist and inhibitor of inflammatory mediators. Animal models with desloratadine have ...

Ten years later, the Swiss-Italian physiologist Daniel Bovet synthesized the first antagonists ... discovery of H1, the number of known histamine receptors kept multiplying. The H2 receptor ...

1942—Antergan becomes the first antihistamine tested in humans and goes on the market. 1972—James Black discovers the H2 receptor and characterizes its antagonist, burimamide. 1999 ...