Researchers from the Leibniz Institute for Natural Product Research and Infection Biology discovered that RNA modifications ...

For example, antifungal agents are often classified into three groups, depending on their site of action: the polyenes interact with fungal membrane–building blocks; azoles inhibit the synthesis ...

Scientists have discovered that the most widely-used class of antifungals in the world causes pathogens to self-destruct. The University of Exeter-led research could help improve ways to protect ...

Currently, there are no clear-cut recommendations for efficacious antifungal combination in these difficult-to-treat mold infections. Data must be supported by adverse event profile and ...

Therapy with coadministration of two or three antifungals has been applied by clinicians in difficult-to-treat infections, which still have no support from randomized, controlled clinical trials.