AMP-activated protein kinase (AMPK) regulates metabolism by sensing changes in the AMP:ATP ratio in eukaryotic cells. The binding of AMP to AMPK and activation of its Ser/Thr protein-kinase domain ...

The transcription factor sex-determining region Y-related high-mobility group-box gene 9 (SOX9) plays a critical role in ...

This innovation builds on the compound’s ability to activate AMP-activated protein kinase (AMPK), a protein vital for maintaining energy balance. Compared to the widely used diabetes drug ...

Previous research has shown that mammals accumulate LCA during calorie restriction and it activates a key molecule involved in metabolism called AMP-activated protein kinase, or AMPK. AMPK ...

The bile acid activates AMP-activated protein kinase ... They anticipated this would act through AMP-activating protein kinase, because AMPK regulates energy balance by promoting production of ATP and ...

CR turns on adenosine monophosphate (AMP)-activated protein kinase (AMPK), an enzyme that helps cells maintain energy balance. AMPK controls signaling pathways that postpone aging, including FOXO ...

Previous studies had demonstrated that mammals accumulate LCA during calorie restriction, activating a key molecule involved in metabolism called AMP-activated protein kinase (AMPK). According to ...

To elucidate the mechanism further, HepG2 cells were treated with an adenosine monophosphate-activated protein kinase (AMPK) inhibitor to test whether SOX9 acts via AMPK activation. SOX9 ...