The site and mechanism for the analgesic effect of acetaminophen has not been determined but is thought to primarily involve central actions. Caffeine is a methylxanthine and CNS stimulant.

The three ingredients in an OTC migraine cocktail, or combination medication, include acetaminophen, aspirin, and caffeine. The three ingredients in an OTC migraine cocktail, or combination ...

However, if you recently placed an OTC drug order at Amazon ... of Healthy Living Migraine Relief, Acetaminophen 250 mg, ...

WASHINGTON, D.C. — On Friday, the Food and Drug Administration (FDA) proposed a new order to address safety concerns related to over-the-counter (OTC) drugs containing acetaminophen. If ...

To date, the U.S. Food and Drug Administration (FDA) and leading medical organizations agree on the safety of acetaminophen, its use during pregnancy, and the information provided on the label." ...

Acetaminophen 250mg, aspirin 250mg, caffeine 65mg; coated caplets. Reye's syndrome. Persistent or unresponsive headache. Hypertension. Cardiovascular disease. Asthma ...