After they had been actively immunized, and with serum antitoxin levels of 0.007 to 0.01 American unit per milliliter, they challenged themselves with "2–3 fatal doses" of tetanus toxin ...

The researchers modified the Aap protein to display a harmless piece of tetanus toxin. They wanted to see if this modification would trigger an immune response and the production of antibodies ...

of fluid tetanus toxoid containing 1 Lf of diphtheria ... mixed with a standardized dose of test toxin at a tenth or a hundredth of a test-dose level, depending on the level of antitoxin sought.

Eccles, J. C., Fatt, P., and Koketsu, K., J. Physiol. (in the press). Eccles, J. C., Fatt, P., and Landgren, S., Aust. J. Sci., 16, 130 (1954).

With a toxoid vaccine, the goal is to condition the immune system to combat not an invading virus or bacteria but rather a toxin produced by that invading virus or bacteria. The tetanus shot is ...

TETANUS toxin is thought to act by suppressing synaptic inhibition 1, and presumably it acts upon some substance at the inhibitory synapses in the grey matter of nervous tissue. As a possible ...