following oral dosing with 100 mg of sumatriptan. This compares with a Cmax of 5 and 16 ng/mL following dosing with a 5- and 20-mg intranasal dose, respectively. The bioavailability is ...
Sumatriptan 5mg, 20mg; per spray. The vascular 5-HT 1 receptor subtype to which sumatriptan binds selectively, and through which it presumably exerts its antimigrainous effect, is present on ...
Triptans are contraindicated in patients with cardiovascular diseases and hypertension. Sumatriptan and others are contraindicated in patients taking monoamine oxidase (MAO) inhibitors or within 2 ...
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