A new study found that supplementing with creatine while resistance training may not have much of an effect on muscle gains. Study participants either took no creatine at all or took 5 grams of creatine each day. The creatine group gained some lean mass at first, but once both groups were resistance training, the differences were insignificant.

New research says creatine may not improve muscle mass. We talked to a creatine researcher and nutritionist to break down exactly what the study found.

The small clinical trial found no difference between those who took the supplement at the recommended dose and those who did not.

In a recent clinical trial, people taking creatine while resistance training didn't add more lean body mass than those taking a placebo.

But new research is challenging its long-held reputation, raising questions about just how effective it really is. The study, published in Nutrients, followed 63 people ages 18 to 50 with a BMI of 30 kg or less through a 12-week resistance-training program.